AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL
About
AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL belongs to a class of medicines called antihypertensives used to treat hypertension (high blood pressure) and reduce the risk of heart attack or stroke in adults. Hypertension is a condition in which the force of blood against the walls of the artery is very high. It will be an addition to the workload of the heart and arteries.
AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL is a combination of three drugs, namely: Amlodipine (calcium channel blocker), Chlorthalidone (diuretic), and Olmesartan medoxomil (angiotensin II receptor blocker). Amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. Chlorthalidone belongs to the class of diuretics (water tablets) that works by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Olmesartan medoxomil works by blocking the action of a hormone called angiotensin II in the body that causes the narrowing of blood vessels leading to high blood pressure. Thereby, AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL widens and relaxes blood vessels. Thus, it lowers high blood pressure.
Take AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL as prescribed by your doctor. You are advised to take AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, headache, swelling of ankles, feet, hands, arms, or legs, low or high blood pressure, stomach upset, or tiredness. Most of these side effects of AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL or any other medicines, please tell your doctor. AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL and consult a doctor. Drive only if you are alert as AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL may cause dizziness or drowsiness. You are recommended to avoid alcohol consumption with AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL as it may increase the risk of low blood pressure.
Uses of AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL
Medicinal Benefits
AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL contains Amlodipine, Chlorthalidone and Olmesartan medoxomil used to treat high blood pressure. Chlorthalidone is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Amlodipine and Olmesartan medoxomil relax and widens blood vessels. Thus, AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL lowers high blood pressure and reduces the risk of stroke, heart attack or other heart problems.
Directions for Use
Storage
Side Effects of AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL
- Dizziness
- Headache
- Low or high blood pressure
- Swelling of ankles, feet, hands, arms or legs
- Stomach upset
- Tiredness
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL or any other medicines, please tell your doctor. AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL and consult a doctor. Avoid taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL if you have low levels of sodium or potassium in blood, gout, kidney stones, Addison’s disease (adrenal gland does not produce sufficient steroids), high blood levels of calcium, severe liver or kidney problems. Drive only if you are alert as AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL may cause dizziness or drowsiness. You are recommended to avoid alcohol consumption with AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL as it may increase the risk of low blood pressure.
Drug Interactions
Drug-Drug Interaction: AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL may interact with non-steroidal anti-inflammatory drugs (aspirin, indomethacin), antimanic drugs (lithium), blood thinner (heparin), cholesterol-lowering medicine (colesevelam hydrochloride, simvastatin), calcium channel blocker (verapamil, diltiazem), antibiotics (erythromycin, clarithromycin, rifampicin), immunosuppressants (tacrolimus, cyclosporine, everolimus, sirolimus, temsirolimus), water pills (amiloride, spironolactone), heart-related medicines (digoxin).
Drug-Food Interaction: AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL may interact with St. John’s wort (herbal remedy to treat depression). Also, avoid taking potassium supplements, and salt substitutes containing potassium, or potassium-rich foods such as bananas, sweet potatoes, nuts and noni juice with AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL as it may result in hyperkalemia (high levels of potassium in the blood) and cause severe adverse effects. Also, AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL may interact with grapefruit juice and increase the levels of AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL in blood.
Drug-Disease Interaction: Avoid taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL if you have low levels of sodium or potassium in the blood, gout, kidney stones, Addison’s disease (adrenal gland does not produce sufficient steroids), high blood levels of calcium, severe liver or kidney problems. If you have diabetes, eye pain or decrease in vision, high cholesterol, low blood pressure, heart, liver, or kidney problems, inform your doctor before taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.
Pregnancy
unsafeAMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL is not recommended for pregnant women as it may cause serious harm to the unborn baby. Please consult a doctor if you are pregnant.
Breast Feeding
unsafeAMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL may be excreted in human milk and harm the baby. Therefore, avoid taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL if you are breastfeeding and consult a doctor.
Driving
cautionAMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL may cause dizziness or drowsiness in some people. Therefore, avoid driving if you feel dizzy or drowsy after taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL.
Liver
cautionTake AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL if you have severe liver disease.
Kidney
cautionTake AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL if you have severe kidney disease.
Children
unsafeAMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL is not recommended for children below 18 years as safety and effectiveness is not established.
Habit Forming
Diet & Lifestyle Advise
Minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations, and the way you react in certain situations and do activities that you enjoy by making time for yourself.
Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.
Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
Quit smoking and avoid the consumption of alcohol.
Special Advise
Monitor your blood pressure regularly and if you notice any fluctuations, please consult a doctor.
Patients Concern
Disease/Condition Glossary
Blood pressure is the measurement of the force that the heart uses to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.
FAQs
AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL is used to treat hypertension (high blood pressure) and reduce the risk of heart attack or stroke in adults.
AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL contains Amlodipine, Chlorthalidone and Olmesartan medoxomil. Chlorthalidone is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Amlodipine and Olmesartan medoxomil relaxes and widens blood vessels. Thus, AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL lowers high blood pressure and reduces the risk of stroke, heart attack or other heart problems.
AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL may increase potassium levels in the blood. Therefore, it is recommended to avoid intake of potassium supplements and foods that are rich in potassium such as bananas, sweet potatoes, nuts and noni juice with AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL as it may result in hyperkalaemia (high levels of potassium in the blood) and cause severe adverse effects such as irregular heartbeat, muscle paralysis and kidney failure. Also, avoid taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL with grapefruit juice as it increases the levels of AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL in blood.
AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL may cause dizziness in some patients. Therefore, if you feel dizzy after taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL, avoid driving or operating heavy machinery.
You are not recommended to take simvastatin with AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL as it may increase the levels of simvastatin in the blood and increase the risk of liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue). However, please consult a doctor before taking other medicines with AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL.
You are not recommended to stop taking AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL without consulting your doctor even if you find symptomatic relief as it may worsen the condition. Therefore, take AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL for as long as your doctor has prescribed it and if you experience any difficulty while using AMLODIPINE+CHLORTHALIDONE+OLMESARTAN MEDOXOMIL, please consult your doctor.
